You can easily find great opportunities on Twitter because 100s of 1000s of people are interacting on Twitter at a particular time, all over the world. Twitter is not only good news and announcements resource, you can find job and business opportunities on Twitter. Most of the times when people using Twitter have a requirement, rather then posting long texts on various websites, they post it on Twitter. If you are following them, great, but even if you are not following, you can easily find their updates using tools mentioned in this post titled How to use Twitter to conduct searches.
But it’s not about merely conducting searches and approaching people. As they say, you should be ready when opportunities knock at your door. To be able to leverage the various Twitter opportunities, you have to become an effective Twitter user.
Further, read Leveraging your opportunities on Twitter.